Un ulteriore studio che dimostra che alte dosi di estratto di the verde in 12 settimane hanno portato ad un importante dimagrimento e a una diminuzione del giro vita così come ha migliorato il rapporto LDL/HDL. Grazie a diversi meccanismi d’azione, sia termogenici che antiossidanti e antiinfiammatori.
Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trialChen IJ1, Liu CY1, Chiu JP1, Hsu CH2.
BACKGROUND AND AIMS:
To examine the effect and safety of high-dose green tea extract (Epigallocatechin gallate, EGCG) at a daily dosage of 856.8 mg on weight reduction and changes of lipid profile and obesity-related hormone peptides in women with central obesity.
We conducted a randomized, double-blind trial registered underClinicalTrials.gov Identifier no. NCT02147041. A total of 115 women with central obesity were screened at our clinic. 102 of them with a body mass index (BMI) ≥ 27 kg/m2 and a waist circumference (WC) ≥ 80 cm were eligible for the study. These women were randomly assigned to either a high-dose green tea group or placebo group. The total treatment time was 12 weeks. The main outcome measures were anthropometric measurements, lipid profiles, and obesity related hormone peptides including leptin, adiponectin, ghrelin, and insulin.
Significant weight loss, from 76.8 ± 11.3 kg to 75.7 ± 11.5 kg (p = 0.025), as well as decreases in BMI (p = 0.018) and waist circumference (p = 0.023) were observed in the treatment group after 12 weeks of high-dose EGCG treatment. This study also demonstrated a consistent trend of decreased total cholesterol, reaching 5.33%, and decreased LDL plasma levels. There was good tolerance of the treatment among subjects without any side effects or adverse events. Significantly lower ghrelin levels and elevated adiponectin levels were detected in the study group than in the placebo group.
12 weeks of treatment with high-dose green tea extract resulted in significant weight loss, reduced waist circumference, and a consistent decrease in total cholesterol and LDL plasma levels without any side effects or adverse effects in women with central obesity. The antiobestic mechanism of high-dose green tea extract might be associated in part with ghrelin secretion inhibition, leading to increased adiponectin levels.
Copyright © 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved
IL THE VERDE REGOLA LA PRODUZIONE DI ESTROGENI INIBENDO GLI ENZIMI AROMATASI a vantaggio di chi soffre di iperestrogenismo Sindrome premestruale, cisti ovariche ecc. comunque sempre legato a dieta, stile di vita ecc
Modulation of aromatase activity by diet polyphenolic compoundsAuthor information
Estrogens are involved in physiological actions related to reproduction, body fat distribution, and maintenance of bone mass and are also related to the pathogenesis of estrogen-dependent cancers. The aim of this work was to study the effect of polyphenols on estrogen synthesis. The effect of polyphenols and polyphenolic-rich beverages on aromatase activity was tested in JAR cells (a choriocarcinoma cell line) through the tritiated water release assay. Some of the tested polyphenols inhibited estrogen production, chrysin being the most potent. Additionally, we observed that red wine, alcohol-free red wine,green tea, and black tea (200 microL/mL) significantly decreased aromatase activity. … In conclusion, polyphenols are able to modulate aromatase activity and, consequently, estrogen synthesis. The knowledge of such interference may help to clarify some of the biological properties attributed to polyphenols and may be useful in prevention/treatment of estrogen-dependent disorders.
J Nutr. 2009 Feb;139(2):310-6. doi: 10.3945/jn.108.098699. Epub 2008 Dec 11.
Un aiuto anche per gli uomini dai polifenoli di diverse piante..e ancora IL THE VERDE INIBISCE LA 5 ALFA REDUTTASE enzima che converte il Testosterone nel più potente Diidrotestosterone DHT responsabile, dell’alopecia androgenetica, iperplasia prostatica benigna e acne. Ricordo che non ci sono pillole magiche o sostanze miracolose, ma in un percorso di salute meglio usare alcune sostanze piuttosto che altre. Tra le sostanze utili anche il Reishi
An update on plant derived anti-androgens
Grant P1, Ramasamy S.
Grant P1, Ramasamy S.
Anti-androgens are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. Disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign prostatic hyperplasia, and endocrine related cancers such as carcinoma of the prostate…. Other agents covered include red reishi, which has been shown to reduce levels 5-alpha reductase, the enzyme that facilitates conversion of testosterone to dihydrotestosterone (DHT)…; green tea, which contains epigallocatechins and also inhibits 5-alpha reductase, thereby reducing the conversion of normal testosterone into the more potent DHT;